National Institute for Health and Care Excellence
Alcohol-use disorders: diagnosis and management of physical complications (CG100)
Clinical guideline · Tier 1, UK official · UK · 2010-06-02, updated 2017-04-12
Current — checked with the publisher on 2026-09-01
https://www.nice.org.uk/guidance/cg100/chapter/Recommendations
What this platform has drawn from it — 5 claims
- NICE CG100 recommends that people who are alcohol dependent but not admitted to hospital are offered advice to avoid a sudden reduction in alcohol intake, and information about how to contact local alcohol support services.
Recommendation 1.1.1.4, section 1.1.1 Admission to hospital
held in the ledger, not rendered on any page - NICE CG100 recommends offering admission to hospital for medically assisted alcohol withdrawal to people in acute alcohol withdrawal who have, or are assessed to be at high risk of developing, alcohol withdrawal seizures or delirium tremens.
Recommendation 1.1.1.1, section 1.1.1 Admission to hospital
held in the ledger, not rendered on any page - NICE CG100 states that phenytoin should not be offered to treat alcohol withdrawal seizures.
Recommendation 1.1.5.3, section 1.1.5 Management of alcohol withdrawal seizures
held in the ledger, not rendered on any page - NICE CG100 recommends offering corticosteroid treatment to people with severe alcohol-related hepatitis and a discriminant function of 32 or more, but only after three conditions are met: effectively treating any active infection or gastrointestinal bleeding, controlling any renal impairment, and discussing the potential benefits and risks with the person and their family members or carers - explaining that corticosteroid treatment has been shown to improve survival in the short term (1 month), has not been shown to improve survival over 3 months to 1 year, and increases the risk of serious infections within the first 3 months of starting treatment. NICE recorded in April 2017 that this was an off-label use of prednisolone.
Recommendation 1.3.3.1 [2017], lead sentence and first two conditions · Recommendation 1.3.3.1 [2017], third condition, lead · Recommendation 1.3.3.1 [2017], third condition, the three points to be explained
held in the ledger, not rendered on any page - NICE CG100 recommends referring patients with decompensated liver disease to be considered for assessment for liver transplantation if they still have decompensated liver disease after best management and 3 months' abstinence from alcohol, and are otherwise suitable candidates for liver transplantation.
Recommendation 1.3.2.1, section 1.3.2 Referral for consideration of liver transplantation
held in the ledger, not rendered on any page
How this record was checked, and what is doubtful about it
Recommendations page fetched and read; no withdrawal banner. The corticosteroid recommendation 1.3.3.1 carries the [2017] marker. Its attached off-label prednisolone note is dated April 2017 and its licensing statement must be re-checked against the current SPC before any content rests on it.
Verification: verified · last accessed 2026-09-01 · status checked against https://www.nice.org.uk/guidance/cg100