Acute upper gastrointestinal bleeding in over 16s: management (CG141)

What this platform has drawn from it — 5 claims

• NICE CG141 recommends offering terlipressin at presentation to patients with suspected variceal bleeding, stopping treatment after definitive haemostasis has been achieved or after 5 days. NICE records that at the time of publication terlipressin was licensed for a maximum treatment duration of 72 hours, so the recommended duration is an off-label use. Recommendation 1.5.1, section 1.5 Management of variceal bleeding · Footnote to recommendation 1.5.1
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• NICE CG141 recommends offering prophylactic antibiotic therapy at presentation to patients with suspected or confirmed variceal bleeding. Recommendation 1.5.2, section 1.5 Management of variceal bleeding
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• NICE CG141 recommends using band ligation in patients with upper gastrointestinal bleeding from oesophageal varices. Recommendation 1.5.3, subheading Oesophageal varices
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• NICE CG141 advises considering transjugular intrahepatic portosystemic shunts (TIPS) if bleeding from oesophageal varices is not controlled by band ligation. Recommendation 1.5.4, subheading Oesophageal varices
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• NICE CG141 recommends offering endoscopic injection of N-butyl-2-cyanoacrylate to patients with upper gastrointestinal bleeding from gastric varices. Recommendation 1.5.5, subheading Gastric varices
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