Extracorporeal whole liver perfusion for acute liver failure (HTG573, formerly IPG690)

Clinical guideline · Tier 1, UK official · UK · 2021-03-31

Current — checked with the publisher on 2026-09-02

https://www.nice.org.uk/guidance/HTG573/chapter/1-Recommendations

What this platform has drawn from it — 1 claim

NICE found that evidence on the safety of extracorporeal whole liver perfusion for acute liver failure shows serious, well-recognised complications and that evidence on efficacy is inadequate in quantity and quality, and therefore restricted the procedure to use only in the context of research. Section 1 Recommendations, recommendation 1.1
read on Extracorporeal liver support

How this record was checked, and what is doubtful about it

Migrated from IPG690 with content unchanged. Note the wording differs from HTG202 in a way that matters: HTG573 restricts the procedure to 'the context of research', while HTG202 permits use under 'special arrangements for clinical governance, consent and audit OR research'. Those are different restrictions and this ledger does not merge them.

Verification: verified · last accessed 2026-09-02 · status checked against https://www.nice.org.uk/guidance/HTG573